Introduction & Final Programme

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Posters

In vitro and in vivo delivery studies of siRNA-peptide conjugates

JJ Turner 1, MM Fabani 1, SW Jones 2, SA Moschos 3, M Perry 3, MA Lindsay 3 and Mike J Gait 1

1. Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. 2. Respiratory and Inflammation, Astrazeneca Pharmaceuticals, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK 3. Departments of Thoracic Medicine and Respiratory Pharmacology, National Heart and Lung Institute, Imperial College School of Medicine, Dovehouse Street, London SW3 6LY, UK

A quantitative cell-based reporter assay for identification of protein components in RNA interference

Lana Dinic, Markus Landthaler and Thomas Tuschl

RNA Molecular Biology, Rockefeller University, New York, NY 10021, USA

Allele-specific silencing of mutant alpha subunit of the muscle acetylcholine receptor: Comparison between pU6- and tRNA val-driven shRNAs.

Angie Biba and David Beeson

University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, UK

Dynamics of antiviral silencing in plants: a model study

Marian Groenenboom and Paulien Hogeweg

University of Utrecht, THE NETHERLANDS

ON- and OFF-target effects in siRNA genomic screens: Problems and solutions

Amanda Birmingham, Emily Anderson, Angela Reynolds, Diane Ilsley, Devin Leake, Yuriy Fedorov, Elena Maksimova, Kathrin Robinson, Jon Karpilow, William Marshall, Anastasia Khvorova

Presenter : Dr Dmitry Samarsky, Director, Technology Development

Dharmacon, Inc., 2650 Crescent Drive #100, Lafayette, CO 80026

Inhibiting HBV gene expression with long hairpin RNA sequences that target the viral x open reading frame

Abdullah Ely, Sergio Carmona, Carol Crowther, Steven Mufamadi, Marc Weinberg and Patrick Arbuthnot

Hepatitis B Virus Research Unit, Department of Molecular Medicine and Haematology, University of the Witwatersrand, SOUTH AFRICA

Improved in vitro transfection of mast cells and RNAi-mediated knockdown of the high-affinity IgE receptor, Fc e RI

Glen Reid, Gill Webster §, Rebecca MacKenzie, Faamatala Aliifaalogo, Fiona Radcliff, Greg Murison

Genesis Research and Development Corporation Limited, PO Box 50, Auckland, NEW ZEALAND

§ current address: Virionyx Corporation Limited, PO Box 91806, Auckland, NEW ZEALAND

MicroRNA expression profiling of Diffuse Large B-cell lymphoma reveals differences between germinal centre-like and activated B cell-like subtypes

Charles H Lawrie 1, Shamit Soneji 2, Christopher Cooper 1, Christian Hatton 3

1. Nuffield Department of Clinical Laboratory Sciences, University of Oxford. 2. Weatherall Institute of Molecular Medicine, University of Oxford. 3. Department of Haematology, John Radcliffe Hospital, Oxford, UK

Interaction of Arsenic Trioxide As 2O3 with RNA and DNA

Shohreh Nafisi 1, Amir Sobhanmanesh 1, Kamran Alimoghaddam 2, Ardeshir Ghavamzadeh 2 and Heidar-Ali Tajmir- Riahi 3

1. Deparment of Chemistry, Azad University, Tehran Central Branch, Tehran, IRAN , 14169 63316. 2. Hematology, Oncology and BMT research Center, Tehran University of Medical Science, Shariati Hospital, Kargar Ave., Tehran, IRAN, 1411713131. 3. Department of Chemistry-Biology, University of Quebec at Trois-Rivieres, C.P. 500, TR, Quebec, CANADA G9A 5H7

Comparison of the activity of siRNAs and shRNAs against furin: A potential cellular target for HIV-1 inhibition

Pavlina Konstantinova, Bart van Heertum, Olivier ter Brake, Rogier Sanders and Ben Berkhout

Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, THE NETHERLANDS

Fucntional inhibition of poly(ADP-Ribose) polymerase by siRNA technique

Antal Topadi 1, Balazs Debreceni 1, Katalin Hanto 2, Zita Bognar 1, Aliz Szbao 1, Balazs Radnai 1, Zsuzsanna Tucsek 1 and Balazs Sumegi 1,3

1 Department of Biochemistry and Medical Chemistry, 2 First Department of Medicine, Division of Cardiology, and, 3 Hungarian Academy of Sciences, Research Group for Mitochondrial Fucntion and Mitochondrial Diseases, University of Pecs Medical School, Pecs, HUNGARY

RNA silencing approach in the rice blast fungus, Magnaporthe oryzae, using an opposing promoter system

Nguyen Bao Quoc , Naoki Kadotani, Yukio Tosa, Shigeyuki Mayama, and Hitoshi Nakayashiki

Laboratory of Plant Pathology, Faculty of Agriculture, Kobe University, 1-1 Rokkodaicho, Nada, 657-8501 Kobe, JAPAN

Prevention of a myocardial pathogen by RNA interference

Denise Werk 1 , Steffen Schubert 1, Vanessa Lindig 2, Hans-Peter Grunert 2, Heinz Zeichhardt 2, Volker A Erdmann 1, Jens Kurreck 1

1 Free University Berlin, Institute for Chemistry (Biochemistry), Thielallee 63, D-14195, Berlin, GERMANY. 2. Charité-University Medicine Berlin, Campus Benjamin Franklin, Institute for Infectious Diseases Medicine, Department of Virology, Hindenburgdamm 27, D-12203 Berlin, GERMANY

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