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Journal of RNAi
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Introduction & Programme
The conference covered a diverse variety of topics in the field, including advances in understanding biology of RNA interference and its applications in gene function analysis and therapy. The conference brought together a diverse mix of participants, including leading experts from both academia and industry, postdoctoral researchers, graduate students and managers. Thus this event provided an excellent opportunity to discover the latest research directions and thinking in this fast moving field in academic and commercial settings as well as to develop new collaborative links.
Conference Programme:
Wednesday 22nd March 2006
7.15 am Registration
8.00 am Welcome
Session I: Chaired by Sumedha Jayasena
8.15 am Kim, V Narry: miRNA processing and its applications in RNAi
8.45 am Jayasena, Sumedha D: MicroRNAs in cancer: Connecting the dots
9.15 am Wiemer, Erik: miRNA expression in cancer cell lines and tumor samples
9.45 am O'Toole, Sharon: miRNA expression signatures in cervical cancer
10.15 am Refreshments, exhibitions & posters
Session II: Chaired by Ronald Plasterk
10.35 am Parker, James: Studies of Argonaute proteins: Central mediators of RNA silencing
11.05 am Keynote: Plasterk, Ronald: MicroRNAs in animal development
12.05 pm Shah, Girish: Abrogation of gene silencing by DNA vector-based RNAi during apoptosis due to cleavage and inactivation of Dicer
12.35 pm Holen, Torgeir: A new mechanism for siRNA inactivation
12.55 pm Lunch break
Session III: Chaired by William Marshall & Georg Sczakiel
2.00 pm Marshall, William: siRNAs: From functional genomics to drugs
2.30 pm Behlke, Mark: Use of Dicer-substrate RNA duplexes in vitro and in vivo
3.00 pm Hannus, Michael: HT-RNAi-based target discovery screen for atherosclerosis using microscopy assay in human hepatoma cells
3.30 pm MacLachlan, Ian: Considerations for the development of siRNA-based drugs
4.00 pm Refreshments, exhibitions & posters
4.20 pm Sczakiel, Georg: Phosphorothioate-stimulated uptake of siRNA by human cells: a progress report
4.50 pm Haedrich, Bettina: The transition of RNAi from a research reagent to a validated tool
5.20 pm Kandimalla, Ekambar: Synthetic oligonucleotides as therapeutic agents
6.00-7.00 pm Drinks reception
7.00 pm Close of Day 1
Thursday 23rd March 2006
8.20 am Welcome
Session IV: Chaired by Ben Berkhout
8.30 am Kurreck, Jens: Multiple approaches to inhibit picornaviruses by RNA interference
9.00 am Berkhout, Ben: RNAi gene therapy to protect cells against HIV-1
9.30 am Song, Erwei: Harnessing RNAi as a novel gene therapy: Targets and delivery
10.00 am Milner, Jo: Molecular mechanisms mediating immune evasion in African trypanosomes: antigenic variation studied using RNAi in place of an immune system
10.30 am Refreshments, exhibitions & posters
Session V: Chaired by David Baulcombe
10.50 am Dickinson, Hugh: RNAi, epigenetics and the plant life cycle
11.20 am Keynote: Baulcombe, David: Small RNA genomics
12.20 pm Margis, Rogerio: The evolution and diversification of Dicers in plants
12.40 pm Lunch break
Session VI: Chaired by Julian Downward
2.00 pm Weinstein, Edward J: Human and murine viral vector-based RNAi libraries for pan-genomic knockdown studies
2.30 pm Downward, Julian: Using genome scale RNA interference screens to investigate oncogenic signaling by Ras in human cells
3.00 pm Cédric, Raoul: The potential of RNAi for neurodegenerative diseases
3.30 pm Refreshments, exhibitions & posters
3.50 pm Rudenko, Gloria: Death without stress
4.20 pm Beeson, David: The neuromuscular synapse: A model system for investigating gene silencing in synaptic transmission
5.00 pm Close of Conference
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*****
This is what some of our delegates said about the conference
"Excellent spectrum of people from a wide variety of locations; good for networking."
"I enjoyed the meeting immensely - a good balance of talks ... industrial talks were nicely scientific and not sales pitches! Let's have it again in 2007"
"Excellent balance of academic and industrial talks."
"An excellent opportunity to network"
"I found the conference very well run and informative - would be pleased to return."
"The meeting was great not only for experts in RNAi but also for students like me."
"Good place, great meeting."
"Excellent conference."
"A very satisfactory meeting, intensive and efficient."
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