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Posters
RNAi and disease in tropical monocot plants
Jennifer Ann Harikrishna, Chuen Yi Foong, Adelene Ai Lian Song, Saw Hoon Lim, Norzulaani Khalid & Rofina Yasmin Othman
Institute of Biological Sciences, Faculty of Science and Centre for Research in Biotechnology for Agriculture (CEBAR), University of Malaya, Kuala Lumpur, Malaysia.
Biotechnology Program, Malaysia University of Science and Technology, Selangor, Malaysia
Keywords: Banana, orchid, CymMV, DCL-1, exogenously applied dsRNA
Critical factors for successful RNAi experiments in primary cells and hard-to transfect cell lines.
Markus Zumbansen, Ludger Altrogge, Dietmar Lenz and Herbert Müller-Hartmann
Research & Development, amaxa GmbH, Cologne, Germany, D-50829
Keywords: siRNA delivery, primary cells, suspension cells, screening
Silencing of the expression of an antiapoptotic protein in cancer treatment - Preclinical data
Piotr Guzenda, Maria Majorek, Aleksandra Pączkowska, Monika Lamparska-Przybysz, Maciej Wieczorek
Laboratory of Molecular Biology, Celon Pharma Diagnostic Clinic, Mokra 41a St.,05-092 Lomianki, Poland
Characterisation of microRNAs in the human heart
Han Lu, Prakash Punjabi, Fatimah Rahman, Paolo Camici, Tim Aitman, Stuart Cook
MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, London W12 0NN, UK
Hammersmith Hospitals NHS Trust, B Block, 2 nd Floor, Du Cane Road, London W12 0HS, UK
Keywords: microRNA, heart, heart failure, diabetes
RNA silencing in virus-infected plants
Thien Ho and Hui Wang
NERC Centre of Ecology and Hydrology, Mansfield Road, Oxford, OX1 3SR, UK
Department of Biochemistry, University of Oxford, OX1 3QU, UK
Inhibition of ECHO virus 30 by RNA interference
D Rothe , S Schubert , D Werk, H Zeichhardt, H-P Grunert, H Fechner, W Poller, V A Erdmann and J Kurreck
Free University Berlin, Institute for Chemistry and Biochemistry, Thielallee 63, 14195 Berlin, Germany, email: drothe@chemie.fu-berlin.de
Department of Virology, Institute for Infectious Diseases Medicine, Charité – Universitätsmedizin Berlin, Campus Benjamin Franklin, 12203 Berlin, Germany
Department of Cardiology & Pneumology, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, 12203 Berlin, Germany
MicroRNA expression in haematological malignancies by expression profiling
Charles H Lawrie, Shamit Soneji, Christopher Cooper, Christian Hatton
Nuffield Department of Clinical Laboratory Sciences, University of Oxford, UK
Institute of Molecular Medicine, University of Oxford, Oxford, UK
Department of Haematology, John Radcliffe Hospital, Oxford, UK
Proof of Concept studies for the application of ‘inducible’ RNAi to silence a specific pathway and increase sensitivity of cellular toxicity screens
Jonathan Hitchcock, Jenny Redelius, Paul Hayter, Mark Fidock, Fiona Spence, Christer Hoog
Drug Safety R&D, Pfizer Global R&D, Sandwich UK
Department of Cell and Molecular Biology, Karolinska Institute, Sweden
Pain Therapeutic Area, Discovery Biology, Pfizer Global R&D, Sandwich UK
Biomarker and Translational Biology, Pfizer Global R&D, Sandwich UK
A foamy-virus system expressing small interfering RNA, for gene knockdown in mammalian cells
M Papadaki, EK Siapati and G Vassilopoulos
Cell and Gene Therapy Lab, Institute for Biomedical Research of the Academy of Athens, 4 Soranou Efesiou str., 115 27, Athens, Greece
Keywords :RNAi, posttranscriptional gene silencing, foamy virus, vector, gene therapy
Decreased expression of microRNAs 143 and 145 in human colon cancers
Yoshihito Nakagawa, Yukihiro Akao1 and Tomoki Naoe
Department of Medical Oncology, Gifu International Institute of Biotechnology , Kakamigahara, Gifu, Japan
Department of Hematology and Oncology, Nagoya University, Graduate school of Medicine, Nagoya, Japan
Keywords: microRNAs-143 and -145, human cancer, onco-miRNAs, ERK5, growth inhibition, apoptosis
Arrest of cancer cells proliferation by anti-myc-siRNA
E L Chernolovsksya, T O Kabilova, A V Vladimirova, V V Vlassov
Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia
Keywords: siRNA, c-myc, neuroblastoma, of-target effects, innate immunity
2’-O methyl modified siRNA long-term inhibitors of gene-expression
A A Volkov, N A Kruglova, A G Ven`yamilova, E L Chernolovskaya, M A Zenkova, and V V Vlassov
Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia
Keywords: siRNA, shRNA, modification, nuclease resistance, gene silencing
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